Abaka.com
Interactive map of Prague that details the locations of some well known hotels around town.
http://www.abaka.com/Czech/Praha_MAP.html

Andel3W
Hotel map of Prague and its suburbs.
http://www.andel3w.dk/antuser/hotels/map.htm

AskMaps.com
Contains a printable index of Prague's streets.
http://www.askmaps.com/001/mm6.php

Athos Travel
Contains a handy online map of Prague as well as a street finder.
http://www.athos.cz/

Atlas.cz
Searchable interactive maps of Prague and the rest of the Czech Republic, as well as a route planner.
http://mapy.atlas.cz/aquariusnet/frm_uvod.asp

Ceroi.net
Maps depicting water, waste, noise, population and more in Prague.
http://www.ceroi.net/reports/prague/backgrnd/maps.htm

Hot Maps
Interactive and zoomable map of central Prague.
http://www.hot-maps.de/europe/czech_republic/prague/homeen.html

Map and Guide Prague
Zoomable map of central Prague.
http://maps.pbj.cz/

Mapy.cz
Excellent interactive map of Prague.
http://www.mapy.cz/

Prague City Breaks.com
Mini guide to the city that includes a basic interactive map.
http://www.praguecitybreaks.com/

Prague - Subway
An easy-to-follow map of the Prague metro system.
http://www.czechsite.com/images/metro.jpg

Square Meal
The top of the page contains a link to a detailed interactive map of Prague that covers areas of the city frequented by tourists.
http://www.squaremeal.cz/

Tiscali.com
Auto maps, cycling maps, tourist maps, distance calculators and interactive maps of Prague and the rest of the country. Unfortunately, the site is only available in Czech.
http://mapy.atlas.cz/aquariusnet/frm_uvod.asp